Greenwood, 17, has made four appearances for United in the Premier League this season but all have come from the substitutes bench and totalled just 47 minutes overall.
Tuanzebe, 21, meanwhile, is yet to feature this term although he has been promoted to third-choice central defender this season behind Harry Maguire and Victor Lindelof.
As well as Greenwood and Tuanzebe, Solskjaer also announced that backup goalkeeper Sergio Romero and Brazilian midfielder Fred would be involved from the start.
Speaking ahead of the game, Solskjaer said: He [Axel Tuanzebe] is going to start. Weve got a big squad, pre-season went really well.
Axel is one who didnt make the starting XI so now it is a chance for them to get some minutes. There will be some young ones tomorrow. Greenwood will play definitely.
Mason is one of the best finishers Ive seen, and Ive played with quite few decent ones.
On Romero, Solskjaer added: Sergio will play tomorrow for sure, hes proven to be a top, top keeper behind David and keep him ready for if something happens to David.
[Its] Time for him to have some much-needed game time.
Fred will alRead More – Source