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The Tass news agency reports that Russian Prime Minister Dmitry Medvedev submitted his resignation to President Vladimir Putin on Wednesday.
Russian media said Putin plans to name Medvedev as deputy of the presidential Security Council.
Medvedev, a longtime close associate of Putin's, has served as Russia's prime minister since 2012. He spent four years before that as president in 2008-2012.
Putin asked the member's of Medvedev's Cabinet to keep working until a new Cabinet is formed.